Lysine is an essential amino acid found in both plant- and animal-based foods that are high in protein. Lysine supplements have been studied for potential health benefits, including cold sore ...

In enzymology, a dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) is an enzyme that catalyzes the chemical reaction Quick Facts Identifiers, EC no. ...

A recent study reveals that a polymer called polyphosphate may stabilize fibrils, protein structures linked to Alzheimer's, ...

Ubiquitylation is the post-translational modification process by which ubiquitin is attached via an isopeptide bond to lysine residues on a protein. Ubiquitylation consists of three steps ...

(c) Hidden unit from an RBM trained on the Pfam DUF2156 domain. The MSA positions 152 and 212 correspond to residues S684 and R742, respectively. (d) Residues (in yellow) in the MprF cytosolic domain ...

YTHDF1 binds to m6A modification sites on SFTSV, decreasing the stability of SFTSV RNA and reducing translation efficiency of SFTSV proteins. SFTSV protein NSs promotes YTHDF1 lactylation to inhibit ...

氨基酸是组成蛋白质的基本单位，其突变可以通过多种方式影响蛋白质功能，进而影响细胞生存和多种疾病的发生发展。此前 ...

研究基于实验室此前开发的赖氨酸功能位点筛选策略，利用腺嘌呤碱基编辑器对全基因组范围内的丝氨酸、苏氨酸和酪氨酸位点进行靶向编辑，并在人类视网膜色素上皮细胞系（RPE1）中进行了细胞筛选，成功鉴定出3,467个功能性氨基酸位点。这些位点的突变展示 ...

Have you been paying attention to current events recently? See how many of these 10 questions you can get right. Compiled by Jeremy Engle and Michael Gonchar As the votes are counted, we invite ...

For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but ...

Food safety is a global challenge with chemical residues in foods causing harm to consumers. In particular, pesticide residues in food value chains is one of the leading causes of toxicities and a ...