Apolipoproteins (apo) such as apoB, apoC and apoE, coat lipoprotein particles and serve a number of functions including the transport of lipids in the blood and recognition of lipoprotein ...
To keep your LDL cholesterol levels in check, balance your plate with lean proteins, veggies and smaller portions of ...
Activity was measured by the amount of free fatty acids released by control or postheparin plasma from an artificial lipoprotein triglyceride substrate during one hour of incubation at 37°C.
Lipoprotein (a) is an independent risk factor for atherosclerotic cardiovascular disease. However, lipoprotein (a) testing remains variable and it is unclear what factors influence testing and if ...
The majority of the VLDL remnants are taken up by the liver via the LDL receptor, and the remaining remnant particles become IDL, a smaller, denser lipoprotein than VLDL. The fate of some of the ...
Low-density lipoprotein cholesterol (LDL-C) and lipoprotein(a) (Lp[a]) levels are independently associated with atherosclerotic cardiovascular disease (ASCVD). However, the relationship between Lp(a) ...
Here, we reveal the role of Ras-related protein Rab-2A (Rab2A) in mediating LD-Golgi interactions, thereby contributing to very-low-density lipoprotein (VLDL) lipidation and secretion in hepatocytes.
Eli Lilly said a Phase 2 clinical trial for its treatment to inhibit lipoprotein(a) formation met its primary endpoint. Eli Lilly said the treatment, a once-daily pill called muvalaplin ...
The ALPACAR trial showed that among patients with ASCVD and elevated lipoprotein(a), zerlasiran reduces lipoprotein(a) by >80%. Patients with ASCVD and elevated lipoprotein(a) were randomized to ...
The KRAKEN trial showed that among patients with high cardiovascular risk and elevated lipoprotein(a), muvalaplin reduces lipoprotein(a) levels. Patients with high cardiovascular risk and elevated ...
Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans fat-induced atherosclerosis - (https:/ ...
HDL is often referred to as “good” cholesterol because it helps to remove LDL cholesterol from the arteries and transport it back to the liver ... which helps reduce the risk of plaque formation and ...