Yet when “naked” RNA is injected, it degrades quickly. To address this issue, scientists have developed, and now widely use, the strategy of encapsulating mRNA into lipid nanoparticles (LNPs).

1 Translational Medicine Research Center, Sirius University of Science and Technology, Sochi, Russia 2 Chemistry Department, Moscow State University, Moscow, Russia Today, lipid nanoparticles (LNPs) ...

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune ...

To create nanoparticles that deliver RNA, Whitehead, professor of chemical engineering and biomedical engineering, uses synthetic lipids. They're comprised of carbons and amines, which contain ...

Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...

The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery. The industry is now poised to exploit the full therapeutic potential ...

This is your definitive industry-led meeting to discover new lipid-based nanoparticle formulations and engineer delivery systems for emerging payloads beyond RNA for extrahepatic delivery.

Despite these benefits, there are still relatively few FDA-approved RNA-based therapies, with the notable exceptions being the mRNA (mRNA) COVID-19 vaccines, which are delivered using lipid ...