It inhibits cytochrome P-450 isoenzyme 1A1 and is metabolized by glucuronidation. [13] Neither turmeric nor curcumin has been extensively studied in clinical trials. One clinical trial compared ...

Figure 1 lists the pharmacokinetic drug interactions with smoking. The most clinically significant interactions appear in the shaded rows and are discussed below.

Objective To clarify the effects of smoking on the disposition of two commonly used antipsychotics, olanzapine and clozapine, and to create standards to adjust the doses of these drugs in clinical ...