In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) ...
Subscribe for FREE Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses.
Scientists have long attempted to create vaccines that coax the immune system into recognizing the fusion (F) proteins present on the surfaces of RSV, hMPV and related viruses. These proteins play ...
This is the RSV fusion glycoprotein is shown (left) in its pre-fusion state in complex with an antibody (red and white ribbon) and (right) in its post-fusion shape. Disclaimer: AAAS and EurekAlert!
“In the prefusion state, the RSV fusion protein (F) is a major target of neutralizing antibodies, serving as the basis of Pfizer’s RSV vaccine. Variations in the F protein sequence among RSV-A and RSV ...
RSV F proteins sit on the viral surface, ready to engage with host cell receptors and regulate the virus's fusion and entry into the host cell. The scientists' images reveal that in RSV ...
Widespread distribution of nirsevimab to infants with respiratory syncytial virus infection raised concerns about potential ...
Most assays target the RSV fusion surface glycoprotein. The color change is mediated by the binding of viral protein from the sample to the test's RSV-specific antibodies. The apparatus ...
Maternal RSV vaccination enhances antibody transfer to newborns, with optimal transfer efficiency observed when given at ...