F. Huxley and R. Niedergerke (1954 ... which states that the sliding of actin past myosin generates muscle tension. Because actin is tethered to structures located at the lateral ends of each ...

Dysregulation of F-actin can lead to changes in cell shapes and biomechanics, which can contribute to a range of diseases including blood disorders, immunodeficiencies, muscle myopathies, cataracts, ...

Methods: Serum samples were obtained from 33 healthy controls and 33 patients with severe skeletal muscle damage, defined by a total creatine kinase value of >500 IU/l (Rosalki method). Troponin I, ...