Intrathecal delivery of MAPK kinase MEK1/2 inhibitor U0126 (10 μg; dissolved in 10 μl 10% dimethyl sulphoxide; Calbiochem, San Diego, California, USA) was performed as previously described.16 Briefly, ...

Over a period of 2.5 years, she underwent numerous installations of dimethyl sulphoxide and alternative regimens of BCG and crystal distension. To manage the pain, she was first prescribed ...

1 Center of Experimental Rheumatology, University Hospital Zurich and Zurich Center of Integrative Human Physiology (ZIHP), Zurich, Switzerland 2 Clinic and Policlinic of Internal Medicine, University ...