In the trial, 20% of patients didn’t respond well to the PCSK9 inhibitor—could genetic markers be used to tailor therapy?

People reporting long-COVID symptoms had elevated levels of cytokines, which are proteins the body makes to fight ...

An infiltration of >30 eosinophils per high-power field in at least five high-power fields, exhibiting signs of eosinophilic degranulation and extending to the muscularis mucosa or submucosa are ...

The adverse event in the earlier clinical trial involved amyotrophic lateral sclerosis, which wasn't related to vaccination.

The lesions in TMEP are not pruritic and do not produce Darier's sign because mast cell proliferation may not be sufficient to produce significant degranulation (Alto & Clarcq, 1999; Hogan & Lewis ...

Interleukins are cytokines produced and secreted mainly by CD3+ and CD4+ T lymphocytes. Interleukins promote development and differentiation of natural killer cells, T and B lymphocytes and ...

Degranulation of the beta cells of the pancreas was also observed. In 1 of these 3 patients with severe nonketotic metabolic acidosis in association with diabetes two episodes of acidosis were ...

Dr. Kita's lab is studying the immunological mechanisms behind many common allergic diseases, including asthma, hay fever, atopic dermatitis, chronic sinusitis, food allergies and drug allergies. Led ...

1 Johns Hopkins University, Rheumatology, Baltimore, United States of America 2 NYU Grossman School of Medicine, Division of Rheumatology, New York, United States of America 3 University of Maryland, ...

Background: Doxorubicin (DR), the most commonly used chemotherapy, results in dose-dependent cardiotoxicity in part by causing oxidative stress, cardiomyocyte death, and cardiac fibrosis. Whether ...

Correspondence to Dr Toshio Kitamura, Division of Cellular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo ...