Aim: The present study aimed to investigate the human genetic diversity of the CYP450 superfamily in order to identify functional interethnic differences and analyze the role of CYP450 enzymes in ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Nonetheless, the vast chemical diversity encompassed by ...

Amsterdam-based Cradle, an AI-powered platform revolutionising protein engineering, has secured $73 million in Series B funding to meet growing demand in research-intensive industries. Led by IVP with ...

A recent study evaluated whether lower esomeprazole doses could achieve therapeutic pH goals while minimizing adverse effects ...

Cytochrome P450 enzymes (P450s) and their redox partner cytochrome P450 reductase (CPR) often perform poorly in bioproduction of natural products by engineered prokaryotic microbes. Here ...

CVKD READ THE FULL CVKD RESEARCH REPORT Business Update Cadrenal Therapeutics, Inc. (NASDAQ:CVKD) is a biopharmaceutical company developing tecarfarin, a late-stage novel oral and reversible ...

A 2023 study showed that different enzymes from the cytochrome P450 family were responsible for metabolism of cannabidiol via ...

Schrödinger has already generated several computational predictive models of off-target drug activity. The company’s recent ...

The triazole class of fungicides are demethylase inhibitors that inhibit lanosterol 14 alpha-demethylases (cytochrome P450 (CYP) enzymes) and disrupt cell membrane biosynthesis. Noteworthy, azole ...

Companies using Cradle’s software have seen up to a 90 per cent reduction in rounds. For example, one biotechnology customer ...