Researchers have discovered that the NMDA receptor (NMDAR), known for its role in learning and memory, also stabilizes brain activity by setting baseline neural network activity.
In cultured sympathetic neurons, GDNF, NRTN and ARTN, by their cognate co-receptors, induce a coordinated phosphorylation of the same four key RET tyrosines (Tyr905, Tyr1015, Tyr1062 and Tyr1096 ...
This movie shows two cultured human neurons expressing ASAP5 demonstrating spontaneous electrical activity. One of the neurons is also being recorded with an electrode (black trace). Electrical ...
This study presents a valuable finding on the molecular mechanisms that govern GABAergic inhibitory synapse function. The authors propose that Endophilin A1 serves as a novel regulator of GABAergic ...
Dr. Antonella Ruggiero studied NMDAR function in cultured neurons using an innovative technique called "dual perturbation," developed in Prof. Slutsky's lab. "First, I exposed neurons to ketamine, a ...