The Hedgehog (Hh) pathway plays central roles in ... Although the connections between cilia, sterols and Hh signalling promise to yield new insights into some of the long-standing questions ...
Yoder also helped break the news that the cilia antennae are responsible for receiving one of the most important signals in the body—the so-called Sonic hedgehog protein, which promotes cell growth.
Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems ...