Elderly: 12.5 mg once daily. Angina pectoris- Adult: Initially, 12.5 mg bid increased to 25 mg bid after 2 days. Heart failure- Adult: Initially, 3.125 mg ... taken twice a day with food.

Although switching is usually safe and well tolerated, physician judgment concerning individual patient requirements must be maintained. The dose of the first- or second-generation β blocker that ...