Some scientists believe the amyloid pathway outside the cell is a consequence ... to be much more toxic to neurons than other amyloid-beta peptides. The Lilly data is from a phase I trial, so ...
This is crucial as the trial’s focus on TREM2 activation, which plays a role in the Amyloid beta pathway associated with Alzheimer’s, could lead to beneficial impacts on brain health beyond amyloid ...
In the triage pathway, a negative blood biomarker test ... Research has shown that amyloid beta and tau protein blood biomarkers — especially a high plasma phosphorylated (p)–tau217 levels ...