New discoveries in atherosclerosis pathways have shed light on the active mechanisms in other diseases such as chronic kidney disease (CKD) and HIV, paving the way for furture therapeutics.

Request permissions for this article. Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston (M.J.H., Z.S.W.). Rheumatology and ...

Atherosclerosis involves multiple processes ... Here we will review the current understanding of the pathophysiological mechanisms and the status of molecular and gene therapeutic approaches ...

Air pollution, especially particulate matter, significantly increases the risk of heart disease. It triggers inflammation and ...

in atherosclerosis. Thus, we sought to comprehensively review the available data on the topic, exploring in particular the pathogenetic mechanisms, and discuss anticipated future directions.

Heart and blood vessel diseases—like heart attacks, heart failure, and strokes—are major health problems worldwide. Experts predict that by 2060, these diseases will become even more common in both ...

Cholesterol crystals (CCs) have a pathogenic role in various cardiovascular diseases, particularly atherosclerosis. In this Review, Boisvert and colleagues describe the mechanisms underlying CC ...

Mapping the link between genetic factors and the cellular composition of atherosclerotic plaques can help predict the future ...

In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits ...