Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1,2,3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates.

(114,116) After that, the acyl-hydrazide dissociates or gets further deacylated to the free hydrazide, but none of these species show as high potency, selectivity, or τ as the original DFMO.

Very long-chain acyl-CoA dehydrogenase deficiency (VLCAD), a rare inherited genetic condition, is caused by mutations in the ACADVL gene. It is associated with a disorder in fatty acid metabolism ...

WE have found that isonicotinic acid hydrazide, a widely used drug 1, is a potent inhibitor of the crosslinking of fibrin. This reaction constitutes the terminal step in normal blood coagulation ...

College of Agriculture and Biology, Liaocheng University, Liaocheng 252000, P. R. China ...