Transmembrane proteins (TPs) are proteins that traverse both the intracellular and extracellular environments and are embedded in the cell membrane. The transmembrane area, which interacts ...

Transmembrane proteins are frequently the primary targets of antibody therapies. Located on the cell membrane, these proteins are readily accessible for antibodies to bind to in the extracellular ...

Transmembrane proteins involve various physiological functions, including protein ligation, recognition, transport, anchoring, and transduction. Several diseases are connected with abnormalities ...

2012;46(7):1065-1075. Class III mutations occur in only a small percentage of patients with CF (2–3%). [1] These mutations are called gating mutations. The CFTR protein reaches the cell membrane ...