Weight reduction has been shown to alleviate symptoms of osteoarthritis of the knee, including pain. The effect of ...

Total hip replacement is routinely recommended for severe hip osteoarthritis, but data from randomized trials are lacking ...

Severe tricuspid regurgitation is associated with disabling symptoms and an increased risk of death. Data regarding outcomes after percutaneous transcatheter tricuspid-valve replacement are needed.

Although lead has been mined for 6000 years, lead processing skyrocketed in the 20th century. 1,8 A malleable and durable metal, lead was used to prevent fuel from burning too quickly and to ...

Hairy-cell leukemia (HCL) is a rare, indolent neoplasm of mature B cells with hairlike surface projections that circulate in the blood and preferentially infiltrate the bone marrow and spleen.

The Race and Medicine collection reflects NEJM’s commitment to understanding and combating racism as a public health and human rights crisis. Our commitment to antiracism includes efforts to ...

Limited fasciectomy is the method most frequently used to correct Dupuytren’s contracture in Europe and the United States. 5-7 Another treatment involves injection of an enzyme, collagenase ...

For patients with asymptomatic severe aortic stenosis and preserved left ventricular ejection fraction, current guidelines recommend routine clinical surveillance every 6 to 12 months. Data from ...

Is obesity-related knee osteoarthritis solely a result of increased mechanical stress on the joint? Osteoarthritis of the knee represents the most prevalent form of osteoarthritis and leads to ...

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