Objectives: To assess the efficacy and tolerability of valsartan and valsartan plus hydrochlorothiazide (HCTZ), given alone or as part of a combination regimen with other antihypertensive agents ...

Most patients received the recommended once daily dose of 80mg valsartan or valsartan/HCTZ 80/12.5mg. On the basis of about 20 000 patient-years, the number of deaths observed in the studies (22 ...

Sulfonamide allergy. Concomitant neprilysin inhibitors (eg, sacubitril); do not administer benazepril/HCT within 36hrs of switching to or from sacubitril/valsartan. Concomitant aliskiren in ...