Early steps of infection by HIV-1 involve entry of the viral core into cells, reverse transcription to form the linear viral DNA, and integration of that DNA into a chromosome of the host.
We therefore developed a strategy to assemble the full–length HIV–1 clones by using PCR–mediated recombination (Fig. 1). The four DNA fragments (A, B, C and D) encompassing the full–length ...
This valuable study uses robust time-dependent microscopy assays to show that during HIV-1 infection, the viral accessory protein Vif causes cell cycle arrest during metaphase and not G2/M as ...
Of these, only 1 percent will work their way into the nuclei ... You have just produced a naked-DNA HIV vaccine. Trials for a genetic vaccine that may protect against AIDS began in 1995.