Zofenopril is a highly lipophilic ACE inhibitor characterised by long-lasting tissue penetration and sustained cardiac ACE inhibition. As shown in preclinical studies, zofenopril has ...

Zofenopril is a prodrug that, once absorbed, undergoes rapid and complete hydrolysis to the sulfhydryl-containing active metabolite zofenoprilat. In healthy volunteers, a single oral dose of ...