seen as a cross-bridge between actin and myosin filaments in muscle, acts as the motor domain of the molecule and pulls actin filaments along by repetitive conformational changes coupled to ATP ...

Methods: Serum samples were obtained from 33 healthy controls and 33 patients with severe skeletal muscle damage, defined by a total creatine kinase value of >500 IU/l (Rosalki method). Troponin I, ...

Dysregulation of F-actin can lead to changes in cell shapes and biomechanics, which can contribute to a range of diseases including blood disorders, immunodeficiencies, muscle myopathies, cataracts, ...

Eggs pop out of ovaries. But what propels them has been unknown. Now, researchers from the University of Connecticut explain in an article published in the September 18 issue of the Proceedings of the ...

and the regulation of cell shape. Our lab’s investigations of cardiac muscle contraction focus on the effects of cardiomyopathy-causing amino acid substitutions on myosin’s mechanical and enzymatic ...