(C) The subregions of a glycerophospholipid molecule; phosphatidylcholine is shown as an example. The hydrophilic head is composed of a choline structure (blue) and a phosphate (orange).

and their membrane proteins play essential roles in many biological processes, but the monolayer lipid membrane of LDs has not been extensively studied due to the lack of suitable molecular probes.

The main functions for lipids are cell membrane structure components (which directly influence the fluidity and solubility of the membrane) signaling molecules for normal cellular functions and ...

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ...

Lipids, or fats, are essential to life. They form the membranes around cells, protecting them from the outside. In nature, ...

Lipid nanoparticles made from lipids optimized via directed chemical evolution show high performance as mRNA delivery vehicles.

Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...