Plus-stranded RNA viruses induce large membrane structures that might support the replication of their genomes. Similarly, cytoplasmic replication of poxviruses (large DNA viruses) occurs in ...
Our hypothesis is that one or more of these cells cause viruses to enter into defective RNA replication mechanisms that result in deletion of up to 50 nucleotides from the 5’ end of the genome. This ...
In the face of the relentless threat posed by highly pathogenic RNA viruses, such as SARS-CoV-2, HIV, and avian influenza, the quest for innovative antiviral therapies has never been more urgent.
Many RNA viruses use pseudoknots in the control of viral RNA translation, replication and the switch between the two processes. Some satellite viruses encode ribozymes with active sites that are ...