Interestingly, the extended PMCA yielded novel forms of misfolded prions that caused new disease phenotypes. When injected into wild-type hamsters, the PMCA-generated hampster PrP Sc caused ...

and chronic wasting disease in deer are all variations of prion diseases, each caused by the same type of misfolded brain ...

May 17, 2024 — A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic wasting disease (CWD ...

"Scrapie" is the old Scottish shepherds' name for a disease of their sheep which has been known for several centuries. It is the original example of a group of diseases, known as the ...

This page is a brief resource for families affected by prion diseases. We understand the challenges and concerns that come with caring for a loved one with this rare and complex condition. This page ...

The center is supported by the CDC and sponsored by the American Association of Neuropathologists. The National Prion Disease Pathology Surveillance Center (NPDPSC) is the only Center of its kind in ...

neurological disease found in deer, elk and moose. Misfolded proteins, or prions, produce behavioral changes, lack of coordination, drooling, drooping ears and drastic weight loss, among other ...