Medically reviewed by Mary Choy, PharmD Biologics work by targeting proteins that cause inflammation in ulcerative colitis.

Ulcerative colitis is a type of chronic inflammatory bowel disease that causes painful ulcers and irritation in the large intestine. In North America alone, it is estimated to affect more than ...

Mirikizumab, a drug currently approved by the Food and Drug Administration (FDA) for the treatment of ulcerative colitis, ...

Medically reviewed by Lindsay Cook, PharmD Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that primarily affects the large intestine (colon). It may also cause signs and ...

Results from a retrospective cohort study show lower all-cause mortality and fewer hospitalizations and intestinal ...

66 and certain CpG preparations can prevent the onset of experimental colitis by inducing the production of type 1 IFN (IFN-α/β) in plasmacytoid dendritic cells, via TLR9 ligation. 67 There is ...

Results provide a mechanistic explanation of why early loss of p53 signaling is frequently observed in UC-associated ...