Researchers have revealed the role of enzyme TYK2 in the aggregation of tau proteins, which contributes to Alzheimer’s ...

Although tau accumulation seems to be secondary to the appearance of beta-amyloid plaques ... theory suggests that the abnormal tau induces phosphorylation in additional proteins leading to ...

In addition to Tau transgenic flies, we will perform functional studies based on expression of the human amyloid-Beta peptide (Aß), which is similarly associated with ... including potential roles in ...

Genentech handed crenezumab and semorinemab, antibodies that respectively target amyloid beta and tau, in the wake of phase 2 and 3 data drops that dampened expectations for the candidates.

The early data also tied trontinemab to significant changes in Alzheimer’s biomarkers, such as total tau, according to Roche. Trontinemab is an amyloid-beta antibody Roche developed using its in ...