Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...

TCGFB, a private biotech founded by healthcare VC The Column Group, is tapping California biotech Surrozen to discover ...

Under the terms of the agreement, Surrozen will provide antibody discovery services for a period of up to two years. TCGFB will own all TGF-β product related intellectual property. In exchange for ...

These functions are regulated by the interplay of various signaling pathways. The TGF-β and HIPPO pathways are particularly relevant due to their roles in tumor suppression and liver regulation.

THRAP3, STMN1, and GNA13—are overrepresented in blood cancers like acute myeloid leukemia (AML) and could prove to be novel ...

Such cellular and non-cellular components of TME have the ability to reprogram the processes of tumor emergence and development by controlling various cascade signaling pathways. Therefore ...

Joan Massagué, PhD, a world leader in research on signaling pathways and transcriptional programs that regulate normal cell behavior ... and importance of his work elucidating the mechanism of action ...

cells with their CTL suppressor function titratable along the PI3K-Akt-Foxo1 signaling pathway to overcome cancer immune tolerance without triggering autoimmunity, which was corroborated in a clinical ...

Substantial enrollment progress in Phase 1b trial of SZN-043 in severe alcohol-associated hepatitis patients with proof-of-concept data expected ...

小RNA转染。包括siRNA转染，miRNA，mimic，inhibitor等。 长链的mRNA和shRNA转染，针对mRNA和长链的shRNA等RNA转染优化。 可转染动物细胞、昆虫细胞等，也可以转染原代细胞、悬浮细胞和原代细胞等传统难转染细胞。 11.J Sex Med. 2011 Oct;8(10):2773-80.Up-regulation of VEGF by ...