gp96 is a powerful immune stimulator that directs antigen cross-presentation and enhances T cell costimulation on activated dendritic cells. “We formed Heat with the singular goal of developing ...

EvolveImmune’s platform builds CD2 costimulation into T-cell engagers. As well as binding to the tumor antigen and T-cell receptor complex, like a standard bispecific, EvolveImmune’s molecules ...

Title: Comprehensive biomarker analyses from a Phase 1 study reveals marked tumor microenvironment modulation in patients with advanced solid tumors treated with MP0317, a FAP-localized CD40 agonistic ...