How rigorous are the criteria used to conclude that complete differentiation of organ-specific stem cells to a heterologous lineage has occurred? For the most part, the lineage-unrelated progeny ...

In the study "Long-term lineage commitment in hematopoietic stem cell gene therapy," published in Nature, the team investigated how stem cells used in gene therapy behave differently depending on ...

Now, new research demonstrates that once stem cells have entered this state, known as lineage plasticity, they cannot ...

Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.

Lineage Cell Therapeutics ... products that may be used in surgery and products for human embryonic stem cell research. The company was founded by Judith Segall, Hal Sternberg, Paul E.

November 21, 2024--(BUSINESS WIRE)--Lineage Cell Therapeutics, Inc. (NYSE American and TASE: LCTX), a clinical-stage biotechnology company developing allogeneic cell therapies for unmet medical ...

Techniques that cause multipotent adult mesenchymal stem cells (MSCs) to differentiate into cells of the chondrogenic lineage have led to a variety of experimental strategies to investigate ...