As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The paradigm of stellate cell activation provides an important framework for defining sites/targets of antifibrotic therapy (Table; see [54] for review). These strategies include: (A) curing the ...

The group found the shape maximizes light absorption and angular coverage when compared to flat-structured cells, suggesting the structure would be beneficial for applications requiring flexible ...

How do Cancer Cells Adopt Different Shapes During Metastasis? The migration of cells is an essential event during organism development and for many functions in the adult organism. For example immune ...

Now, an international team of mathematicians has discovered a new class of shapes capable of tiling with a minimal amount of ...

We are focused on understanding how gene regulation occurs through novel mechanisms of mRNA translation. Specifically, we study how non-canonical translation pathways shape cell growth and ...

How cells changing their shape or moving orchestrate their cytoskeleton? Cells and tissues are not static structures, but during development they change their size and shape and migrate. Plasticity of ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...

When that occurs, cell signaling becomes hyperactive and indiscriminate. Zhang explains, "Different microdomains control ...