Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more ...

The endogenous pathway involves the liver synthesizing lipoproteins. TG and cholesterol ester are generated by the liver and packaged into VLDL particles and then released into the circulation.

Our objective is the elucidation of signalling pathways with an impact on cholesterol metabolism regulation. Specifically, we aim to discover novel genes and their encoded products that could ...