Cyclin-dependent kinase 5, a serine/threonine kinase, contributes to neurodegeneration in Parkinson's disease. This kinase is now shown to phosphorylate peroxiredoxin-2, inactivating it ...

AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

The V600E missense mutation in the cytosolic serine–threonine kinase BRAF leads to its constitutive activation (independently of upstream regulation by RAS at the plasma membrane, as shown in ...

Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...

This system utilizes a high content peptide microarray containing phosphorylatable tyrosine (PTK chip) or serine/threonine (STK chip) residues within kinase substrates. Active kinases within a sample ...

No writing assistance was utilized in the production of this manuscript. BRAF, a member of a serine/threonine kinase protein family, serves as an immediate downstream effector of RAS in the MAPK ...

Co. Ltd. has patented new tricyclic compounds acting as serine/threonine-protein kinase ATR inhibitors and thus reported to be useful for the treatment of colon cancer.

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

In a report released today, Silvan Tuerkcan from JMP Securities maintained a Buy rating on Acrivon Therapeutics, Inc. (ACRV – Research ...

§ p = 0.0001 between temsirolimus and IFN-α. ¶ p = 0.0001. # p = 0.0001. ** p = 0.001. NR: Not reported; ORR: Overall response rate; OS: Overall survival; PFS ...

In a report released today, Soumit Roy from JonesTrading maintained a Buy rating on Acrivon Therapeutics, Inc. (ACRV – Research Report), ...

Herpesviruses are common co-pathogens in individuals infected with human immunodeficiency virus (HIV). Herpes simplex virus ...