Whereas mouse Apc knockouts mostly develop tumors ... one has been able to manage to derive ES cells capable of forming rat chimeras. The problem: researchers were stuck on using the same cell ...

But creating chimeras for other tissues, like neural tissue, is more complex. Researchers at the University of Texas Southwestern Medical Center previously grew mice with partial rats’ brains.

After approval of investigator’s approach, the core will initiate electroporation in mouse ES cells. Investigator-screened targeted clones will be expanded by the core, sent for chromosome counts, and ...

Scientists at Queen Mary University of London and the University of Hong Kong have created a mouse with substituted genes from a single-celled organism known as a choanoflagellate. Scientists replaced ...