the antisense strand has to be incorporated into the RNA-induced silencing complex (RISC). It turns out that the relatively low thermodynamic stability in the 5′ end of the antisense siRNA ...

值得一提的是，除了实现基因沉默，新的研究表明 microRNA 也能与细胞中介导基因沉默的组分（RNA-induced silencing complex）之外的生物大分子互作 ...

and RNA-induced silencing complex (RISC) complex. Sixfold applied this to the extracellular space, hypothesizing that modifications are dictating the delivery mechanism and destination by altering ...

这一机制通常涉及肿瘤细胞内源性的双链RNA（dsRNA）及其感应器。感应器识别异常的dsRNA信号后，诱导干扰素（IFN）反应，从而促进抗肿瘤免疫 ...

记者10月10日从中山大学获悉，中山大学医学院施莽教授团队与阿里云李兆融团队在《细胞》杂志（Cell）发表的论文报告了全球范围的180个超群、16万余种的RNA病毒发现，大幅扩展了全球RNA病毒的多样性。 该研究将人工智能技术应用于病毒鉴定，发现了传统研究 ...

incorporates into the RNA-induced silencing complex (RISC), causing unwinding of its double strand. The sense strand of siRNA is then removed from RISC, and the activated RISC with the antisense ...

Androgenetic alopecia (AGA) is the leading cause of hair loss in both men and women. Experts outline current and emerging ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair ... We recently solved a 2.2 Å crystal structure of the Candida Trl1 kinase domain in complex with GDP and Mg ...

This discovery, along with the identification of other nitrogenous bases, laid the foundation for our understanding of DNA and RNA structure. Cytosine can be synthesized chemically ... This ...

Africa Renewal is a United Nations digital magazine that covers Africa’s economic, social and political developments. We cover the challenges the continent faces and the solutions to these by ...

In haploid organisms, including bacteria, archaea, viruses, and mitochondria, a cell contains only a single set of the genome, usually in a single circular or contiguous linear DNA (or RNA for ...

Drug-induced lupus is more common in men because they are given these drugs more often; however, not everyone who takes these drugs will develop the disease. Specific criteria for diagnosing ...