Past efforts to develop CoV vaccines have used whole-inactivated virus, live-attenuated virus, recombinant protein subunit, or genetic approaches. CoV spike (S) proteins mediate cellular ...
HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...
A subunit vaccine makes use of just a small portion of a pathogen. For a virus, the vaccine can contain just a piece of the protein coat that surrounds the virus's DNA (or RNA). Even small portion ...
MPA-CF 3 specifically binds to COPZ1, a subunit of COPI. Upon binding, MPA-CF 3 destabilizes COPZ1 and disrupts the interaction of COPZ1 with the EV-A71 2C protein in a concentration-dependent manner.
The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize the overall structure of the ribosome. One of the most remarkable features of rRNA is its catalytic activity ...
Avidity Biosciences Inc. has announced two new precision cardiology development candidates targeting rare genetic cardiomyopathies. AOC-1086 targets phospholamban (PLN) cardiomyopathy and AOC-1072 ...