For the peptide to inhibit Huntington’s disease, it needs to cross the blood-brain barrier in large enough quantities to prevent large-scale protein aggregation. “The peptide has a very small ...
For the peptide to inhibit Huntington's disease, it needs to cross the blood-brain barrier in large enough quantities to prevent large-scale protein aggregation. "The peptide has a very small ...
Protein aggregation is the process by which misfolded proteins adopt a conformation that cause its polymerization into aggregates and organized fibrils. Many neurodegenerative diseases ...
They measured the compounds' activity to inhibit protein aggregation at the micromolar ... "These compounds cross the blood-brain barrier and reach the brain in rodent models, which is a big ...
A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the ...