Protein aggregation diseases are not exclusive to the central nervous system; they can also appear in peripheral tissues. In general, the genes and protein products involved in these kinds of ...

So, we started thinking about a new way to address this disease. The misfolded proteins interact and aggregate. We’ve developed a polymer that can fight those interactions.” The new study builds on ...

Researchers have identified that G-quadruplexes promote harmful protein aggregation in neurodegenerative diseases. Blocking ...

Proteins are essential components of cellular life, uniquely translating genetic information into a vast array of molecular ...

For the peptide to inhibit Huntington's disease, it needs to cross the blood-brain barrier in large enough quantities to prevent large-scale protein aggregation. "The peptide has a very small ...

Scientists at Northwestern, and Case Western Reserve universities have developed the first polymer-based therapeutic for the genetic disorder Huntington’s disease, an incurable neurodegenerative ...

For the peptide to inhibit Huntington's disease, it needs to cross the blood-brain barrier in large enough quantities to ...

Scientists at La Trobe University have created a world-first method to investigate "disordered" proteins in living cells, in ...

Parkinson’s disease is a brain disorder that affects about one million people in the U.S. It happens when the brain loses ...

A team of researchers at Kumamoto University has uncovered a mechanism in the formation of harmful protein aggregates that ...

Researchers have revealed the role of enzyme TYK2 in the aggregation of tau proteins, which contributes to Alzheimer’s ...

Neurizon's lead drug NUZ-001 and its major active metabolite significantly and dose-dependently prevented the aggregation of TAR DNA-binding protein 43 (TDP-43) by ~50% and ~55% respectively, in M337V ...