These enzymes and their downstream targets constitute ... This hydrolysis is catalysed by cytosolic phospholipase A2 (cPLA2). Ca 2+-induced cPLA2 lipase action is the rate-limiting step in ...
Corticosteroids have a variety of ocular effects which include inhibition of enzyme phospholipase A2, thereby reducing the endogenous production of PGs and leukotrienes. Steroids and PGs have ...
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