Danish biotech Gubra announces that Germany’s Boehringer Ingelheim has decided to discontinue the development of the long-acting neuropeptide Y receptor type 2 (NPY2R) agonist BI 1820237 in obesity.

Experts suggest that testing for this protein, called neuropeptide Y (NPY), could help predict how heart failure is likely to progress. Researchers hope a blood test could be used to help guide ...

Researchers uncover a link between impaired glutathione–ascorbate metabolism and early dopamine increases in Huntington's ...

The best characterized pathways are the orexigenic neuropeptide Y/Agouti-related protein and the anorexigenic pro-opiomelanocortin/cocaine- and amphetamine-related transcript neurons in the ...

By receiving ghrelin, the hypothalamus in the brain senses hunger and produces 'hunger signaling' through the action of neuropeptide Y (NPY). The hunger signaling activates neurons in the ...

The hypothalamus integrates neurohormonal signaling from gut and adipose tissue. Specific hypothalamic nuclei, including the dorsomedial nucleus (DMN), paraventricular nucleus (PVN) and ...

A new cheap and simple blood test could help identify people who are at the highest risk of dying from heart failure, research suggests. The study found that patients with highest levels of a specific ...

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Deciphering how mammals respond to sensations through their fur could inspire further research on skin sensitivity.

Physiol Behav 101:494-502.[PubMed] [Content] Shalev U, Erb S, Shaham Y (2010) Role of CRF and other neuropeptides in stress-induced reinstatement of drug seeking. Brain Res 1314:15-28. [PubMed] ...

Scordilis’ research interests are in molecular physiology, myogenesis and sexual dimorphism of skeletal muscle. Ordered, regulated movement is one of the distinguishing characteristics of life. In ...