The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine ...
在大脑的神秘世界中,神经干细胞(Neural Stem Cells, NSC)的静息和增殖之间的微妙平衡至关重要。这种平衡不仅影响成人神经发生和体内平衡,还决定了大脑能否有效地修复和再生。小的泛素相关修饰物(SUMO, Small Ubiquitin ...
Researchers have uncovered the crucial role of a protein subunit, INST10, in guiding pluripotent stem cells toward becoming ...
CRISPR-Cas9筛选技术在肿瘤学领域的应用已经取得了显著进展。通过构建全基因组敲除文库,研究者可以系统地鉴定出驱动癌症发生发展的关键基因。例如,研究者可以通过CRISPR-Cas9技术在肿瘤细胞中进行基因敲除,筛选出对肿瘤生长和转移至关重要的基 ...
Researchers have shed new light on the biological processes behind neural cell development, which is fundamental for ...
Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of detail in the ...
The Wistar Institute's Alessandro Gardini, Ph.D. , and lab have shed new light on how certain biological processes determine the development of ...
When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and ...
The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine ...
Researchers at the Joint Department of Biomedical Engineering at UNC and North Carolina State University recently received a $3.15 million grant from the National Cancer Institute.
In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...
该治疗新策略不仅证明了移植人多能干细胞来源的皮层神经元可在结构和功能层面准确修复缺氧缺血性脑病受损的皮层神经环路,且有效降低了移植物过度增殖的风险,极大提高了干细胞移植治疗的安全性。该研究为脑中风/缺氧缺血性脑损伤等神经系统疾病的细胞替代治疗提供了一 ...