triggered by NMDA receptor activation. Although signaling pathways necessary for LTD induction have been identified, those responsible for the regulated internalization of AMPA receptors are unknown.

The neurotransmitter receptor NMDA is also commonly involved in reward pathways and strengthening connections between brain regions. The researchers found that male mice were using NMDA receptors ...

A fatal, highly hereditary illness with no disease-modifying treatments, Huntington’s is long overdue for a therapeutic win.

This study presents a valuable finding on the molecular mechanisms that govern GABAergic inhibitory synapse function. The authors propose that Endophilin A1 serves as a novel regulator of GABAergic ...

Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, USA ...

The past four years have brought disappointment for the Huntington’s community, but optimism is growing as companies ...

More information: Osvaldo Artimagnella et al, Foxg1 regulates translation of neocortical neuronal genes, including the main NMDA receptor subunit gene, Grin1, BMC Biology (2024). DOI: 10.1186 ...

The pathways diagram (Academic career pathway diagram (PDF, 89kB)) shows the three pathways and roles, including accepted promotion and movement routes.‌‌ The clinical career pathways are sub-sets, ...

The MSc Education (Open Pathway) allows you to design your own programme of study based on your areas of interest, rather than choosing one subject area from our specialist pathways. Units can be ...

Pathways to Banking and Finance is a financial access scheme which takes place across two years and supports Year 12 and 13 students who are interested in studying finance or a career in the financial ...

Mental health treatment has evolved significantly over the years, offering new hope for individuals dealing with conditions ...