A second limitation to ENU mutagenesis is that G1 mice are expected to carry quite a few recessive lethal mutations, which make the litter size of G3 colonies much smaller than expected and ...

The study said there was strong evidence that the virus had passed from humans to mice and then – after multiple mutations – had made the reverse journey. The study said the Omicron variant ...

About a million people worldwide have autism originating in mutation in SHANK3 gene; researchers say findings may lead to ...

The newly reported studies demonstrated that the antibodies, in a T cell engager format, can effectively kill cancer cells expressing relevant HER2 mutations both in vitro, and in a mouse ...

Researchers used mitochondrial gene editing to model genetic disorders in mice, revealing profound impacts on brain function, ...

A gene that causes accelerated reproductive aging is directly tied to the risk of miscarriage in younger women, a new ...

Mitochondria possess their own DNA (mtDNA), which plays important roles in cellular respiration and energy consumption.

A new study led by Harvard Medical School researchers shed new light on how even a single defective copy of the ...

Liver-specific SMN1 gene therapy both improved liver functioning, and also reduced other SMA-like symptoms in a mouse model ...

Autism-linked SHANK3 gene mutations disrupt not only neurons but also oligodendrocytes, essential for producing myelin, which ...