MCR = mineralocorticoid receptor. Vesna D Garovic is an attending physician in the Division of Nephrology and Hypertension at Mayo Clinic, and Assistant Professor of Medicine, Mayo Medical School ...
True resistant hypertension is relatively frequent ... Spironolactone inhibits the effects of aldosterone by binding to the mineralocorticoid receptor. Both insulin resistance and obesity have ...
This case illustrates that in cases where secondary hypertension is a consideration, measurement of renin can be invaluable, particularly when mineralocorticoid hypertension is present.
Abiraterone use for prostate cancer can cause mineralocorticoid excess syndrome (MES; eg, hypertension and hypokalemia). Prednisone mitigates these effects; however, the optimal dose level is unclear.
Image Source: Zacks Investment Research The investigational candidate, ocedurenone, is a novel third-generation non-steroidal mineralocorticoid ... with uncontrolled hypertension and advanced ...
cholesterol the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart the molecular pathogenesis of ...
11Beta-hydroxylase deficiency and other syndromes of mineralocorticoid excess as a rare cause of endocrine hypertension. Horm Metab Res 2012; 44: 867–78 CrossRef MEDLINE ...