They further demonstrated that clearance of the inflammatory macrophages led to the diminution of both T cells and dendritic cells, thus allowing the inflammation to become quiescent. Macrophages ...
Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...
Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse ...
Multicellular organisms are a mosaic of different cells, tissues, and systems, each with their own specific function and interactions with other cells within the organism and/or the larger environment ...
Dendritic cells (DCs) actively participate in maintaining this balance. Under steady-state conditions, DCs remain in an immature state and do not mount an immune response against circulating self ...
Resolution Therapeutics has raised £63.5m ($83.3m) in a Series B financing round to develop its macrophage cell therapies. The UK-based company plans to use the money to finance the Phase I/II ...