Interest in lysosomal storage diseases (LSDs) has increased significantly, because several new therapeutics received FDA approval in 2003. Though long overlooked by most major pharmaceutical ...

These observations open the door to more in-depth investigations looking into a potential mechanistic link between TMEM106b aggregation and pathological processes in neurodegeneration,” Rothstein ...

Recent studies suggest that these granules can "hitch a ride" from lysosome ... could be related to the neurodegeneration associated with various disorders, including Alzheimer's Disease and ...

which is one of the most common lysosomal storage disorders, health specialists have detailed this rare disease. Sanofi South Africa and Africa Medical Head, Pharma said that Raising awareness ...

This breakthrough could eventually lead to treatments for diseases like frontotemporal ... is a phospholipid that is located in lysosomes—the cell's garbage bins. "BMP is a co-factor for ...

Credit: Getty Images. Laura Buch, MSPAS, PA-C, emphasizes the need for newborn screening to detect infantile-onset lysosomal storage diseases and swift treatment. In honor of PA Week 2024 ...

helps to protect both mitochondria and lysosomes. “Modulation of HKDC1 function could prevent cellular senescence which is ...

Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome rich enterocytes (LREs). The gut microbiome has ...

In a paper published in National Science Review, a collaborative team of scientists report the development of a ...

They completed the challenge to raise funds for those impacted by Lysosomal storage diseases (LSDs). For engineer Lee, 48, who has been the Malaysia Lysosomal Diseases Association (MLDA ...

Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk of developing Alzheimer's disease later ... the autophagy-lysosome pathway ...