Identification of these diglycine-containing lysine residues has been the basis of many studies reporting ubiquitination sites, as documented by the fact that a search for 'mass spectrometry' and ...

A recent study reveals that a polymer called polyphosphate may stabilize fibrils, protein structures linked to Alzheimer's, ...

氨基酸是组成蛋白质的基本单位，其突变可以通过多种方式影响蛋白质功能，进而影响细胞生存和多种疾病的发生发展。此前 ...

研究基于实验室此前开发的赖氨酸功能位点筛选策略，利用腺嘌呤碱基编辑器对全基因组范围内的丝氨酸、苏氨酸和酪氨酸位点进行靶向编辑，并在人类视网膜色素上皮细胞系（RPE1）中进行了细胞筛选，成功鉴定出3,467个功能性氨基酸位点。这些位点的突变展示 ...

Ensuring food safety and quality is a central public health concern. Food can be contaminated by toxic metals, pesticides and veterinary drug residues, as well as organic pollutants, radionuclides and ...

"The challenge [in modifying peptide structures] lies in achieving site-selective modification, particularly in the presence ...

Among the available options, lysine clonixinate (LC) and naproxen sodium (NS) have proved effective in migraine. The aim of this study was to compare the efficacy and tolerability of oral ...

For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but ...

“Residues required for phosphorylation of translation initiation factor eIF2alpha ... “A bifunctional intronic element regulates the expression of the arginine/lysine transporter Cat-1 via mechanisms ...

Have you been paying attention to current events recently? See how many of these 10 questions you can get right. Compiled by Jeremy Engle and Michael Gonchar As the votes are counted, we invite ...