Future Cardiol. 2012;8(5):707-728. †More torsemide and bumetanide reaches the tubular fluid in patients with liver disease due to a prolonged half-life. ‡Furosemide accumulates in renal ...
Physiologic alterations in CHF, such as changes in absorption, distribution, metabolism, and elimination of drugs, can indeed alter loop diuretic pharmacokinetics; however, these effects do not ...
In patients who do not respond to aldosterone antagonists alone, the addition of a loop diuretic is recommended; however, for patients with recurrent ascites, receiving a combination of agents ...