The study showed that live internalizing cells actively participate in the invasion process ... environment and are detached from the normal matrix. There is definitely more to entosis than ...

Tumor invasion and angiogenesis are reduced ... directly impairs a molecular mechanism active in degradation of extracellular matrix. We would go further, and suggest that the activity of the ...

we seek to establish if the intracellular pressure generation machinery in metastatic cells is abnormal compared to primary fibroblasts and test the hypothesis that defective pressure regulation ...

The extracellular matrix (ECM) is a complex network of secreted proteins ... investigating how the internalisation of ECM components control breast cancer cell invasion. Using a combination of ...

We are particularly interested in the components of the extracellular matrix (ECM) that are important for therapy resistance and how these change during aging. We are also working to understand the ...