Although this high-throughput approach promises to produce more structures of human membrane proteins, it will still exclude many interesting proteins, says Stroud. Its efficiency relies on ...
“Many of the most clinically interesting proteins may be quite scarce in a sample.” SomaLogic is tackling this problem by assembling libraries of ‘slow off-rate modified aptamers’, or ...
The faculty in the workshop discussed the approaches needed to prepare materials for proteomics analysis and the challenges of working with the huge dynamic range of the proteins. Following discovery ...
However, using an unbiased proteomic screening approach, his team unexpectedly discovered a set of accumulated RNA-binding proteins in the nucleus: NONO and SFPQ. "They're interesting proteins ...