The interaction between CD2 and CD58 is critical for forming the immunological synapse, which is pivotal in immune cell activation and adhesion, as well as signaling in both immune and target cells.
A new analysis technique The team developed a method dubbed Computational Immune Synapse Analysis (CISA) which detects not only which cells within a tissue contact each other physically ...
How might the immune system take advantage of the B cell synapse to optimize the effectiveness of encounters between B cells and soluble toxin or circulating viruses? The answer may lie ...
A new analysis technique The team developed a method dubbed Computational Immune Synapse Analysis (CISA) which detects not only which cells within a tissue contact each other physically ...
The team developed a method dubbed Computational Immune Synapse Analysis (CISA) which detects not only which cells within a ...
CTLs and NK cells kill by forming a stereotyped interface with their targets, known as a cytolytic immunological synapse, into which they secrete a mixture of toxic perforin and granzymes. Our ...
The CD2-CD58 axis is associated with the regulation of autoimmune diseases, immune evasion of tumors, antiviral responses, and immune rejection, and targeted therapies for this have been developed.